The development of aquaculture requires the integrated approach of different technological challenges. Between them, control of reproduction of fish is one of the key steps in the process of domestication of the species for cultivation, and is a of the main bottlenecks for the growth and diversification of the sector. On this day we will address how biotechnology can offer solutions for the control of the reproduction of fish species of aquaculture interest thus solving different problems associated with reproductive dysfunctions, protocols of fertilization and quality of gametes.